I'd question whether with a 22" barrel the difference really is 250ft/sec
I'm comfortably 2800ft/sec with 180s from my 22" 3006.
The 300 wm is really gonna want a 24+ to get max performance. With some googlefu at 22" 300wm is 100ft/sec slower than a 24+
I think you will find a 180 from a 22" 300 win mag is around 2900ft/sec.
Now for 210gr vlds. A bit different.
But for 180s definitely wouldn't bother